CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18447
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureCN3225722 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00447487 Functional Category Bioactive
Superfamily Beta-lactamase and Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily
Class Class 1435

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Presenilin-1 and Presenilin-2 inhibitor 4-chloro-N-phenyl-N-[1... 1 12
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 14
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[3-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447489 CHEMBL560059 Bioactive SureCN3209287
CFAMM00447487 CHEMBL552056 Bioactive SureCN3225722
CFAMM00447485 CHEMBL550554 Bioactive (2R)-1-[2-chloro-4-(difluoromethoxy)phenyl]sulfonyl-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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