CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1845
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benzenesulfonamido)-3-[[4-(2-piperidin-4-ylethoxy)benzoyl]amino]propanoic acid family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00328139 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 4
Class Class 511

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Stromelysin-1 Inhibitor PG-530742 Family 4 23
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-[2-[[3-[... 7 0
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073U... 4 6
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Integrin beta-3 and Integrin alpha-IIb inhibitor [(1R)-1-(benz... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


External ID

Functional Category

Molecule Name

CFAMM00328125 CHEMBL122000 Bioactive SureCN244700
CFAMM00328139 CHEMBL1956158 Bioactive (2R)-2-(benzenesulfonamido)-3-[[4-(2-piperidin-4-ylethoxy)benzoyl]amino]propanoic acid
CFAMM00328131 CHEMBL333019 Bioactive (2S)-2-(benzenesulfonamido)-3-[[4-[2-(diaminomethylideneamino)ethoxy]benzoyl]amino]propanoic acid
CFAMM00328127 CHEMBL59562 Bioactive (2S)-2-(benzenesulfonamido)-3-[[4-(2-piperidin-4-ylethoxy)benzoyl]amino]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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