CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18459
Family Name Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]methyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]propanoic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00447545 Functional Category Bioactive
Superfamily Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha Binder Superfamily 7
Class Class 3040

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Prostaglandin E synthase 2 inhibitor AGN-PC-075D2E family 1 0
Cysteinyl leukotriene receptor 1 ligand AGN-PC-07C44I family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447545 CHEMBL550859 Bioactive 3-[5-[[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]methyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27265 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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