CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18462
Family Name Neuronal acetylcholine receptor subunit alpha-3 and Neuronal acetylcholine receptor subunit alpha-4 ligand 2-chloro-3-[(6-chloropyridin-3-yl)methoxy]-5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]pyridine family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00447563 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-4 and Cytochrome P450 1A2 Binder Superfamily
Class Class 1004

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Pyridostigmine Family 5 197
Neuronal acetylcholine receptor subunit alpha-4 Ligand Isproni... 49 172
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 ... 4 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447563 CHEMBL551062 Bioactive 2-chloro-3-[(6-chloropyridin-3-yl)methoxy]-5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]pyridine
CFAMM00447562 CHEMBL563479 Bioactive 2-chloro-3-[(2-fluoropyridin-4-yl)methoxy]-5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridine
CFAMM00447560 CHEMBL563831 Bioactive 2-chloro-3-[(6-chloropyridin-3-yl)methoxy]-5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridine
CFAMM00447559 CHEMBL560788 Bioactive 2-chloro-3-[(2-fluoropyridin-4-yl)methoxy]-5-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27265 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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