CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18470
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhibitor AGN-PC-014VFI family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00447588 Functional Category Bioactive
Superfamily Cathepsin K Inhibitor Odanacatib Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
DNA Binder Procarbazine Family 8 358
Cathepsin K Inhibitor Odanacatib Family 33 84
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
C-C chemokine receptor type 2 ligand SureCN2988733 family 14 17
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 1
Acetylcholinesterase inhibitor N-[2-(1-benzylpiperidin-4-yl)et... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Replication protein E1 inhibitor AC1LAK2U family 3 10
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 12 5
Prothrombin and Coagulation factor X inhibitor [(1R)-5-amino-1... 2 3
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
C-C chemokine receptor type 2 ligand AGN-PC-03L0X5 family 13 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
C-C chemokine receptor type 2 ligand AGN-PC-03L0Z6 family 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447586 CHEMBL551338 Bioactive SureCN5947583
CFAMM00447585 CHEMBL562081 Bioactive AGN-PC-076IWW
CFAMM00447588 CHEMBL556716 Bioactive AGN-PC-014VFI
CFAMM00447587 CHEMBL556717 Bioactive 4-cyano-N-[(3S)-3-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)propyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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