CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18474
Family Name Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor SureCN2205515 family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00140697 Functional Category Bioactive
Superfamily Aurora kinase A and Survival motor neuron protein Binder Superfamily
Class Class 4185

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Aurora kinase A inhibitor AGN-PC-0A9UUA family 4 1
Mast/stem cell growth factor receptor Kit and Proto-oncogene t... 3 5
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 4
Adenosine receptor A3 ligand SureCN6716937 family 1 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 2 0
Aurora kinase A inhibitor SureCN2205392 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00447600 CHEMBL552385 Bioactive SureCN2205554
CFAMM00447599 CHEMBL551633 Bioactive SureCN2204682
CFAMM00447598 CHEMBL564459 Bioactive SureCN2203222

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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