CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18489
Family Name 5-hydroxytryptamine receptor 4 ligand 4-amino-5-chloro-N-[1-[8-[2-(1H-indol-3-yl)ethyl-methylamino]octyl]piperidin-4-yl]-2-methoxybenzamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00447665 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Mu-type opioid receptor Ligand N Alpha-amidino-tyr(me)-pro-trp-p-cl-phe-nh2 Superfamily
Class Class 897

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
5-hydroxytryptamine receptor 4 ligand AGN-PC-00GB52 family 5 2
5-hydroxytryptamine receptor 4 ligand 2-(4-pyridin-4-ylpiperaz... 2 1
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 3
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 2
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Platelet-derived growth factor receptor beta and Vascular endo... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447666 CHEMBL561278 Bioactive 4-amino-5-chloro-N-[1-[5-[2-(1H-indol-3-yl)ethyl-methylamino]pentyl]piperidin-4-yl]-2-methoxybenzamide
CFAMM00447665 CHEMBL552484 Bioactive 4-amino-5-chloro-N-[1-[8-[2-(1H-indol-3-yl)ethyl-methylamino]octyl]piperidin-4-yl]-2-methoxybenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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