CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18496
Family Name Prothrombin and Proteinase-activated receptor 1 ligand (2S)-N-cyclopentyl-N-methyl-5-[4-(methylamino)phenyl]-2-[(4-propylphenyl)sulfonylamino]pent-4-ynamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00447768 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Beta-lactamase Binder Superfamily 6
Class Class 1554

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Interstitial collagenase and Neutrophil collagenase inhibitor ... 3 9
Chymotrypsin-like elastase family member 1 and Neutrophil elas... 1 12
Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[1-(ethyl... 27 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 7 0
Orexin receptor type 2 ligand SureCN1039013 family 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
Prothrombin inhibitor (2S)-3-[4-[amino(hydrazinyl)methyl]pheny... 1 0
Motilin receptor ligand N-[5-[[7-[(4-butylphenyl)sulfonylamino... 1 0
Chymase and Chymotrypsinogen A inhibitor SureCN7836048 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00447768 CHEMBL553108 Bioactive (2S)-N-cyclopentyl-N-methyl-5-[4-(methylamino)phenyl]-2-[(4-propylphenyl)sulfonylamino]pent-4-ynamide
CFAMM00447764 CHEMBL7587 Bioactive (2S)-N-cyclopentyl-N-methyl-5-[4-(methylamino)phenyl]-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)pent-4-ynamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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