CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18502
Family Name Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chloro-6-fluoroquinolin-2-yl)ethenyl]phenyl]methyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]propanoic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00447789 Functional Category Bioactive
Superfamily Cysteinyl leukotriene receptor 1 Binder Superfamily 2
Class Class 1005

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase Inhibitor Licofelone Family 2 6
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
NS5B protein inhibitor AC1NQMYP family 5 0
Substance-P receptor ligand SureCN7796965 family 9 1
Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 l... 3 17
Prostaglandin D2 receptor 2 ligand 2-[3-[(3-chlorophenyl)-meth... 1 0
Thromboxane-A synthase inhibitor 5-Chloro-1-methyl-2-(3-pyridy... 1 0
Prostaglandin E synthase 2 inhibitor AGN-PC-075D2E family 1 0


External ID

Functional Category

Molecule Name

CFAMM00447786 CHEMBL562383 Bioactive AGN-PC-07C4M0
CFAMM00447789 CHEMBL558638 Bioactive 3-[5-[[3-[(E)-2-(7-chloro-6-fluoroquinolin-2-yl)ethenyl]phenyl]methyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]propanoic acid
CFAMM00447788 CHEMBL554154 Bioactive 2-[1-[[5-[[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]methyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]methyl]cyclopropyl]acetic acid
CFAMM00447787 CHEMBL562524 Bioactive (E)-4-[5-[[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]methyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]but-2-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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