CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18505
Family Name Melanin-concentrating hormone receptor 1 and Potassium voltage-gated channel subfamily H member 2 ligand N-[(2,4-dichlorophenyl)methyl]-4-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperazine-1-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00447794 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C Ligand 6-chloro-n-(pyridin-3-yl)indoline-1-carboxamide Superfamily
Class Class 88

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
Amg 423 family 7 47
ABC294640 family 5 75
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 9 31
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Prostaglandin E synthase inhibitor AGN-PC-09QHBK family 3 1
Prostaglandin E synthase and Aldo-keto reductase family 1 memb... 3 12
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chlo... 1 4
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 6 3
P2X purinoceptor 7 inhibitor SureCN1635928 family 4 4
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2
Melanin-concentrating hormone receptor 1 ligand SureCN4917950 ... 3 5
Sterol O-acyltransferase 1 inhibitor SureCN7073167 family 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447794 CHEMBL554511 Bioactive N-[(2,4-dichlorophenyl)methyl]-4-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperazine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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