CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1852
Family Name Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N,N-dimethyl-1,1-diphenylpropan-2-amine family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00328198 Functional Category Bioactive
Superfamily Substance-P receptor Binder Superfamily 3
Class Class 231

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Substance-P receptor Ligand SCH-388714 Family 26 8
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Substance-P receptor ligand 1-[4-[[3,5-bis(trifluoromethyl)phe... 5 8
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-p... 3 0
Substance-P receptor ligand 1-[[(1R,2R,3S)-3-[[3,5-bis(trifluo... 4 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand 1-[(1R,2S,3S)-3-[[3,5-bis(trifluor... 7 2
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Substance-P receptor and Neuromedin-K receptor ligand 3-[[(1R)... 1 2
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 1
Substance-P receptor and Sodium-dependent serotonin transporte... 6 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Substance-P receptor ligand SureCN8415737 family 3 4
Substance-P receptor ligand methyl 2-[(2S,3S)-2-[[3,5-bis(trif... 1 1
Substance-P receptor ligand AGN-PC-02K8GG family 1 1
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Substance-P receptor ligand SureCN8912140 family 2 12
Substance-P receptor and Voltage-dependent L-type calcium chan... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328198 CHEMBL122119 Bioactive (2S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N,N-dimethyl-1,1-diphenylpropan-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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