CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18524
Family Name 5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine receptor 2A ligand SureCN6698809 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00178775 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 10
Class Class 1350

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor Ligand Ro-11-04253 Family 1 1
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Transient receptor potential cation channel subfamily V member... 3 15
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 2 0
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
C-C chemokine receptor type 3 ligand 1-[(3R)-1-[(6-fluoronapht... 2 6
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9818603 f... 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 6-[2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26195 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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