CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18525
Family Name P2Y purinoceptor 12 inhibitor (4S)-4-[(4,6-diphenylpyridine-2-carbonyl)amino]-5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00447903 Functional Category Bioactive
Superfamily P2Y purinoceptor 12 Binder Superfamily 3
Class Class 639

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
Neuromedin-K receptor Ligand SB222200 Family 17 235
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
CP-18770 family 6 27
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Cholecystokinin receptor type A ligand A-65186 family 2 6
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Pol polyprotein and Protease inhibitor Palinavir family 1 0
Pol polyprotein and Cathepsin D inhibitor N-[(1S)-1-[(2R,3S)-3... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Pol polyprotein inhibitor (2S,4S,5S)-5-acetamido-6-cyclohexyl-... 3 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
5-hydroxytryptamine receptor 3A ligand 3-methyl-N-[7-[[3-methy... 2 0
Hematopoietic prostaglandin D synthase inhibitor 4-(3-methylis... 1 7
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Neuromedin-K receptor and Potassium voltage-gated channel subf... 13 2
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Motilin receptor ligand SureCN2768052 family 3 0
Histone deacetylase 1 inhibitor (2S)-N'-hydroxy-2-(pyridine-2-... 3 0
Pol polyprotein inhibitor AC1LALGZ family 2 14
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-[3-(dimethylamino)... 106 49
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-(2-aminoethyl)pipe... 17 2
P2Y purinoceptor 12 inhibitor (4S)-4-[[6-[4-[2-(methylamino)-2... 51 8
P2Y purinoceptor 12 inhibitor pentyl 4-[(2S)-5-[(2-methylpropa... 18 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447903 CHEMBL557553 Bioactive (4S)-4-[(4,6-diphenylpyridine-2-carbonyl)amino]-5-[4-(3-methylphenyl)piperazin-1-yl]-5-oxopentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26233 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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