CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18527
Family Name Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor TAB family
No. of Seeds 1 No. of Other Members 14
Family Centroid CFAMM00447927 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase Binder Superfamily 5
Class Class 4724

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 12
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447927 CHEMBL55764 Bioactive TAB

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27650 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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