CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1853
Family Name Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand (E)-3-[4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-phenylnaphthalen-2-yl]prop-2-enoic acid family
No. of Seeds 3 No. of Other Members 13
Family Centroid CFAMM00328218 Functional Category Bioactive
Superfamily Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Binder Superfamily 3
Class Class 852

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Haloperidol Family 5 53
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Angiotensin-converting enzyme Inhibitor N-carboxymethyl-n-cycl... 2 24
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
C-C chemokine receptor type 5 ligand AC1L9U8N family 8 6
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 2-[4-[[1-(2,... 2 7
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 1 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 1 5
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 3 0
Type-2 angiotensin II receptor ligand SureCN3515167 family 2 0
Pol polyprotein inhibitor Enantiomer of AG1284 family 7 1
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0
Oxytocin receptor and Vasopressin V1a receptor ligand N-(cyclo... 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328218 CHEMBL125559 Bioactive (E)-3-[4-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-8-phenylnaphthalen-2-yl]prop-2-enoic acid
CFAMM00328211 CHEMBL122134 Bioactive SureCN9023482
CFAMM00328210 CHEMBL125723 Bioactive SureCN9023335

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24638 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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