CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18542
Family Name Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzenesulfonamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00447988 Functional Category Bioactive
Superfamily Histamine H3 receptor and Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily
Class Class 2606

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Acetylcholinesterase Inhibitor 1-benzene Sulfonyl-cis-2,6-dime... 1 4
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (1S,5... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 6
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 14 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
C-C chemokine receptor type 5 ligand AC1L9YN4 family 2 33
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Lanosterol synthase inhibitor (E)-but-2-enedioic acid;N-[4-[5-... 1 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00447990 CHEMBL560140 Bioactive 4-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonyl-1,4-thiazinane 1,1-dioxide
CFAMM00447989 CHEMBL562629 Bioactive 1-[4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]phenyl]sulfonylpiperidine
CFAMM00447988 CHEMBL560799 Bioactive N,N-diethyl-4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzenesulfonamide
CFAMM00447987 CHEMBL558923 Bioactive 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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