CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18548
Family Name B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN1565000 family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00448007 Functional Category Bioactive
Superfamily Fibroblast growth factor receptor Binder Superfamily
Class Class 1322

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
PF-02545920 family 16 140
Fibroblast growth factor receptor Ligand LY2874455 Family 1 1
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
D(2) dopamine receptor Ligand SLV-314 Family 19 69
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 4
Translocator protein inhibitor SureCN13502542 family 20 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 6
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 9 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Histone deacetylase 1 and Potassium voltage-gated channel subf... 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-075G9A... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 0
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Platelet-derived growth factor receptor beta and Receptor-type... 1 2
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
RAC-alpha serine/threonine-protein kinase inhibitor N-[(2S)-1-... 2 1
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Platelet-derived growth factor receptor beta and Macrophage co... 8 0
Platelet-derived growth factor receptor beta and Macrophage co... 7 0
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Translocator protein inhibitor N-methyl-2-(2-oxo-5-pyridin-4-y... 8 15
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand Piper... 3 14
Neuronal acetylcholine receptor subunit alpha-7 ligand 5-[6-[[... 1 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 5 14
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4806204 f... 13 7
Serine/threonine-protein kinase Chk1 and Aurora kinase B inhib... 14 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 7-met... 2 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 5 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 3 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
B2 bradykinin receptor ligand SureCN13145573 family 7 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Nischarin inhibitor SureCN7810370 family 1 0
RAC-alpha serine/threonine-protein kinase and Rho-associated p... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Adenosine receptor A1 ligand 4-amino-2-phenyl-3H-pyrazolo[3,4-... 1 0
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448008 CHEMBL559565 Bioactive SureCN13145530
CFAMM00448007 CHEMBL559506 Bioactive SureCN1565000
CFAMM00448006 CHEMBL563956 Bioactive SureCN1563916
CFAMM00448005 CHEMBL559825 Bioactive SureCN13145771

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543