CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1855
Family Name Prothrombin inhibitor N-cyclohexyl-3-[3-(diaminomethylideneamino)oxypropoxy]-N-ethyl-5-methylbenzamide family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00328232 Functional Category Bioactive
Superfamily Prothrombin Binder Superfamily
Class Class 989

Cousin Family NamesSeedsMembers
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 14
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Prothrombin inhibitor 3-[3-(diaminomethylideneamino)oxypropoxy... 6 3
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Prothrombin inhibitor methyl 3-[[3-chloro-5-[3-(diaminomethyli... 1 6
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328230 CHEMBL122205 Bioactive N-(6-amino-6-oxohexyl)-N-cyclohexyl-3-[3-(diaminomethylideneamino)oxypropoxy]-5-methylbenzamide
CFAMM00328229 CHEMBL123226 Bioactive AGN-PC-0752GA
CFAMM00328232 CHEMBL122144 Bioactive N-cyclohexyl-3-[3-(diaminomethylideneamino)oxypropoxy]-N-ethyl-5-methylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26223 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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