CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18552
Family Name Neutrophil elastase inhibitor 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamoyl]naphthalene-2-carboxylic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00448019 Functional Category Bioactive
Superfamily Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Neutrophil elastase Inhibitor FK-706 Family 8 85
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 F... 6 8
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-2-[4-(4-fluor... 1 0
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
Neutrophil elastase inhibitor SureCN7273831 family 2 2
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448019 CHEMBL55963 Bioactive 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamoyl]naphthalene-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26828 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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