CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18557
Family Name Aurora kinase A inhibitor SureCN2205392 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00448031 Functional Category Bioactive
Superfamily Aurora kinase A and Survival motor neuron protein Binder Superfamily
Class Class 4185

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Type-1 angiotensin II receptor Ligand Tasosartan Family 10 29
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Histamine H4 receptor Ligand A-943931 Family 14 11
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(4-a... 8 11
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 4
Aurora kinase A inhibitor AGN-PC-0A9UUA family 4 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 7
Mast/stem cell growth factor receptor Kit and Proto-oncogene t... 3 5
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-met... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Corticotropin-releasing factor receptor 1 ligand 4-[7-(dipropy... 1 1
Adenosine receptor A3 ligand SureCN6716937 family 1 0
Type-1B angiotensin II receptor ligand SureCN9309010 family 5 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 3
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 7 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448031 CHEMBL559900 Bioactive SureCN2205392
CFAMM00448030 CHEMBL72833 Bioactive AGN-PC-074HNH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26857 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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