CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1857
Family Name Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor 1A ligand AGN-PC-064YYK family
No. of Seeds 7 No. of Other Members 10
Family Centroid CFAMM00212763 Functional Category Bioactive
Superfamily Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor Binder Superfamily
Class Class 1435

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-0A9RI2 family 2 2
Sigma non-opioid intracellular receptor 1 ligand N-[6-[[5-[3-(... 1 1
Neuropeptide Y receptor type 5 ligand N-[[4-[2-[7-(trifluorome... 1 1
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Growth hormone secretagogue receptor type 1 ligand SureCN47965... 3 1
Growth hormone secretagogue receptor type 1 ligand SureCN48028... 7 0
Growth hormone secretagogue receptor type 1 ligand SureCN47962... 8 0
Growth hormone secretagogue receptor type 1 ligand SureCN48020... 3 0
Growth hormone secretagogue receptor type 1 ligand SureCN47975... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
Substance-P receptor ligand CP 141938 family 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328265 CHEMBL1258607 Bioactive AGN-PC-087TYT
CFAMM00328262 CHEMBL2364391 Bioactive SureCN4801727

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26195 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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