CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18593
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-({(2s)-1-[(3r)-3-Amino-4-(3-Chlorophenyl)butanoyl]pyrrolidin-2-Yl}methyl)-3-(Methylsulfonyl)benzamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00448103 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-6124 Superfamily
Class Class 1214

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Cathepsin K Inhibitor Odanacatib Family 33 84
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
C-C chemokine receptor type 2 ligand SureCN2988733 family 14 17
C-C chemokine receptor type 5 ligand N-[(1S)-3-[(3aS,6aR)-5-(2... 1 1
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
C-C chemokine receptor type 5 ligand AC1NUL29 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448103 CHEMBL564249 Bioactive N-({(2s)-1-[(3r)-3-Amino-4-(3-Chlorophenyl)butanoyl]pyrrolidin-2-Yl}methyl)-3-(Methylsulfonyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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