CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18598
Family Name Bifunctional epoxide hydrolase 2 and Potassium voltage-gated channel subfamily H member 2 ligand N-(2-phenylcyclopropyl)-4-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00448135 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Bifunctional epoxide hydrolase 2 Binder Superfamily
Class Class 1234

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Transient receptor potential cation channel subfamily V member... 15 457
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Translocator protein Inhibitor Emapunil Family 7 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
GDC-0349 family 44 77
Histone deacetylase Inhibitor JNJ-26481585 Family 2 5
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Prothrombin inhibitor SureCN5856722 family 3 16
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family 13 8
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
RAC-alpha serine/threonine-protein kinase inhibitor (2S)-3-ami... 2 0
Prelamin-A/C and Putative fructose-1,6-bisphosphate aldolase i... 1 7
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... 1 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 12
Signal transducer and activator of transcription 6 inhibitor A... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... 2 8
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Sonic hedgehog protein and Smoothened homolog inhibitor N-(4,4... 2 13
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-isoquinolin-1-y... 3 2
Cathepsin K inhibitor CHEMBL2163360 family 1 0
Bone morphogenetic protein 1 inhibitor (3R)-6-cyclohexyl-N-hyd... 3 7
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Cathepsin K inhibitor SureCN4138062 family 7 0
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[[3-(2-aminoet... 8 7
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... 5 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(9-... 7 4
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor Su... 4 0
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448135 CHEMBL564757 Bioactive N-(2-phenylcyclopropyl)-4-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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