CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18609
Family Name Glucocorticoid receptor ligand SureCN12238714 family
No. of Seeds 16 No. of Other Members 4
Family Centroid CFAMM00448223 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Progesterone receptor Binder Superfamily 10
Class Class 5264

Cousin Family NamesSeedsMembers
TOK-001 family 2 7
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Progesterone receptor and Glucocorticoid receptor ligand SureC... 4 2
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Bombesin receptor subtype-3 ligand SureCN3500939 family 2 2
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 2 10
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... 1 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
Insulin-like growth factor 1 receptor ligand 3-[8-amino-1-(4-e... 9 0
Glucocorticoid receptor and Progesterone receptor ligand SureC... 6 1
Serine/threonine-protein kinase mTOR inhibitor 3-(cyclohexylme... 2 1


External ID

Functional Category

Molecule Name

CFAMM00448233 CHEMBL566600 Bioactive SureCN12238725
CFAMM00448239 CHEMBL565320 Bioactive SureCN12238700
CFAMM00448232 CHEMBL572355 Bioactive SureCN12238734
CFAMM00448225 CHEMBL576472 Bioactive SureCN12238709
CFAMM00448231 CHEMBL572357 Bioactive SureCN12238721
CFAMM00448237 CHEMBL566387 Bioactive SureCN12238711
CFAMM00448230 CHEMBL569061 Bioactive SureCN2543987
CFAMM00448223 CHEMBL569544 Bioactive SureCN12238714
CFAMM00448236 CHEMBL566823 Bioactive SureCN12238724
CFAMM00448229 CHEMBL566575 Bioactive SureCN12238708
CFAMM00448235 CHEMBL577945 Bioactive SureCN12238691
CFAMM00448228 CHEMBL584522 Bioactive SureCN12238701
CFAMM00448241 CHEMBL583625 Bioactive SureCN12238723
CFAMM00448227 CHEMBL572212 Bioactive SureCN12238710
CFAMM00448240 CHEMBL567237 Bioactive SureCN12238702

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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