CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18625
Family Name Melanin-concentrating hormone receptor 1 and Potassium voltage-gated channel subfamily H member 2 ligand (Z)-1-(3,4-difluorophenyl)-1-[4-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]phenyl]-N-methoxymethanimine family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00448377 Functional Category Bioactive
Superfamily Substance-P receptor and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 900

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 5 69
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapol Family 3 41
Substance-P receptor ligand (1S,2R)-2-[(1R)-1-[3,5-bis(trifluo... 7 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 4
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 2
Platelet-activating factor receptor ligand SureCN9575051 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00448377 CHEMBL566880 Bioactive (Z)-1-(3,4-difluorophenyl)-1-[4-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]phenyl]-N-methoxymethanimine
CFAMM00448376 CHEMBL585509 Bioactive AGN-PC-07CRGI
CFAMM00448375 CHEMBL565614 Bioactive (NE)-N-[(3,4-difluorophenyl)-[4-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]phenyl]methylidene]hydroxylamine
CFAMM00448381 CHEMBL582792 Bioactive (Z)-1-(3,4-difluorophenyl)-N-ethoxy-1-[5-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]pyridin-2-yl]methanimine
CFAMM00448374 CHEMBL585856 Bioactive AGN-PC-07CRGL
CFAMM00448380 CHEMBL568571 Bioactive (Z)-1-(3,4-difluorophenyl)-N-ethoxy-1-[4-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]phenyl]methanimine
CFAMM00448378 CHEMBL582978 Bioactive (NZ)-N-[(3,4-difluorophenyl)-[4-[(6-fluorospiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl]phenyl]methylidene]hydroxylamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



46455 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543