CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18635
Family Name Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00448458 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Estrogen receptor beta Binder Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Inosine-5'-monophosphate dehydrogenase 2 inhibitor [2-[N-methy... 1 18
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Glycogen synthase kinase-3 beta inhibitor oxadiazole derivativ... 4 6
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Neuropeptide Y receptor type 5 ligand CHEMBL483239 family 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Platelet-activating factor receptor ligand 2-[4-(2-methylimida... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448460 CHEMBL565882 Bioactive AGN-PC-077D4C
CFAMM00448458 CHEMBL583933 Bioactive AGN-PC-077D0D
CFAMM00448457 CHEMBL569195 Bioactive 2-[4-(1,3,4-oxadiazol-2-yl)phenyl]-1H-benzimidazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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