CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18637
Family Name Metabotropic glutamate receptor 1 ligand AGN-PC-07CPMZ family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00448461 Functional Category Bioactive
Superfamily Substance-P receptor Ligand TAK-637 Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Prothrombin Inhibitor Ximelegatran Family 8 157
Neuromedin-K receptor Ligand SB222200 Family 17 235
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
Pixantrone family 2 3
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 3 5
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... 20 37
Metabotropic glutamate receptor 1 ligand GTPL6334 family 6 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Cathepsin S inhibitor N-[(S)-[1-(1-cyanocyclopropyl)triazol-4-... 1 0
Cannabinoid receptor 1 and Cytochrome P450 3A4 ligand N-(oxan-... 2 0
Metabotropic glutamate receptor 1 ligand 4-[1-(2-fluoropyridin... 1 0
Prolyl endopeptidase inhibitor 4-phenyl-1-[(2S,4S)-4-(4-pyridi... 2 1
Steroid hormone receptor ERR1 ligand methyl 3-[4-(2-aminobenzo... 4 2
Metabotropic glutamate receptor 5 ligand 3-methyl-1-[2-[3-(tri... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448461 CHEMBL565943 Bioactive AGN-PC-07CPMZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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