CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18644
Family Name Cannabinoid receptor 2 ligand AGN-PC-07CRHA family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00448499 Functional Category Bioactive
Superfamily DNA-dependent protein kinase catalytic subunit Inhibitor 2-morpholinobenzo[h]quinolin-4(1h)-one Superfamily
Class Class 1006

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 1 Inhibitor Pyroxamide Family 4 13
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Class II cytokine receptor Ligand IL-10 Family 7 45
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 1
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
D-amino-acid oxidase and D-aspartate oxidase inhibitor naphthy... 2 2
Transient receptor potential cation channel subfamily V member... 3 2
Hormone-sensitive lipase inhibitor AGN-PC-074W3L family 1 2
Farnesyl pyrophosphate synthase inhibitor [phosphono-[[4-(prop... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448493 CHEMBL566057 Bioactive AGN-PC-07CRJT
CFAMM00448500 CHEMBL570792 Bioactive AGN-PC-04UJJ5
CFAMM00448499 CHEMBL567942 Bioactive AGN-PC-07CRHA
CFAMM00448496 CHEMBL568564 Bioactive AGN-PC-04UM5J

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46045 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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