CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18648
Family Name Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[5-fluoro-1-(imidazo[1,2-a]pyridin-2-ylmethyl)-3-methylindol-7-yl]prop-2-enamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00448509 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Serine/threonine-protein kinase mTOR Binder Superfamily
Class Class 853

Cousin Family NamesSeedsMembers
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Platelet-activating factor receptor ligand 6-(4-fluorophenyl)-... 1 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NS1A family 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448509 CHEMBL566202 Bioactive (E)-N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[5-fluoro-1-(imidazo[1,2-a]pyridin-2-ylmethyl)-3-methylindol-7-yl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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