CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18651
Family Name Receptor tyrosine-protein kinase erbB-2 and Disintegrin and metalloproteinase domain-containing protein 10 ligand methyl (2S,3S,5S)-3-(hydroxycarbamoyl)-2-(4-phenylpiperazine-1-carbonyl)-5-(pyrrolidine-1-carbonyloxy)piperidine-1-carboxylate family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00448529 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 10 and Disintegrin Binder Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5


External ID

Functional Category

Molecule Name

CFAMM00448536 CHEMBL572302 Bioactive [(3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl] azepane-1-carboxylate
CFAMM00448529 CHEMBL585886 Bioactive methyl (2S,3S,5S)-3-(hydroxycarbamoyl)-2-(4-phenylpiperazine-1-carbonyl)-5-(pyrrolidine-1-carbonyloxy)piperidine-1-carboxylate
CFAMM00448534 CHEMBL572091 Bioactive [(3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl] 2,5-dihydropyrrole-1-carboxylate
CFAMM00448531 CHEMBL584116 Bioactive [(3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl] piperidine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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