CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18653
Family Name Prostaglandin E synthase inhibitor AGN-PC-04SSMB family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00448541 Functional Category Bioactive
Superfamily Prostaglandin E synthase and cGMP-inhibited 3',5'-cyclic phosphodiesterase A Binder Superfamily
Class Class 5265

Cousin Family NamesSeedsMembers
Tryptase Inhibitor Babim Family 12 90
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Transient receptor potential cation channel subfamily M member... 9 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Neuropeptide Y receptor type 5 ligand SureCN6835211 family 1 2
Prostaglandin E synthase inhibitor AGN-PC-00EMT0 family 7 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Prostaglandin E synthase inhibitor AGN-PC-04SSUG family 3 0
Prostaglandin E synthase inhibitor AGN-PC-07CRKH family 1 0


External ID

Functional Category

Molecule Name

CFAMM00448545 CHEMBL585110 Bioactive AGN-PC-04SSW0
CFAMM00448544 CHEMBL566261 Bioactive AGN-PC-07CRKJ
CFAMM00448543 CHEMBL568545 Bioactive AGN-PC-07CRLB
CFAMM00448542 CHEMBL585486 Bioactive AGN-PC-04SSXH
CFAMM00448541 CHEMBL584932 Bioactive AGN-PC-04SSMB
CFAMM00448540 CHEMBL568125 Bioactive AGN-PC-04ST1O

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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