CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18657
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand Fimx family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00448568 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Cellular tumor antigen p53 Binder Superfamily 4
Class Class 3131

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
DNA primase Inhibitor Bay 57-1293 Family 1 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 26
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
cAMP-dependent protein kinase catalytic subunit beta and cAMP-... 2 9
Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-... 1 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
P2X purinoceptor 7 inhibitor SureCN110930 family 2 0
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)imidazo[1,... 5 3
Thrombopoietin receptor ligand N-[4-[2-fluoro-3-(trifluorometh... 2 14
C-C chemokine receptor type 2 ligand AGN-PC-0765RZ family 1 0
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Histone deacetylase 1 inhibitor SureCN1066177 family 1 1
Tyrosyl-DNA phosphodiesterase 1 and ATP-dependent molecular ch... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448569 CHEMBL577729 Bioactive N-[4-(6-aminopyrimidin-4-yl)-1,3-thiazol-2-yl]-4-fluoro-N-methylbenzamide
CFAMM00448568 CHEMBL569270 Bioactive Fimx
CFAMM00448572 CHEMBL566581 Bioactive 4-fluoro-N-methyl-N-[4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]benzamide
CFAMM00448571 CHEMBL568991 Bioactive AGN-PC-00RXE6
CFAMM00448570 CHEMBL566374 Bioactive AGN-PC-0143RO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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