CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18666
Family Name Glutaminyl-peptide cyclotransferase inhibitor 1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea family
No. of Seeds 1 No. of Other Members 17
Family Centroid CFAMM00448656 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine receptor 3A Binder Superfamily 4
Class Class 1671

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
Nitric oxide synthase, inducible Inhibitor 4-(1h-imidazol-1-yl... 1 7
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Platelet-derived growth factor receptor beta and Platelet-deri... 2 19
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 2 2
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448656 CHEMBL566563 Bioactive 1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27056 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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