CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18692
Family Name Prostaglandin E synthase inhibitor AGN-PC-00C2TD family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00448798 Functional Category Bioactive
Superfamily Smoothened homolog and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
HCV NS4B protein Inhibitor Clemizole Family 2 43
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 3 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Transient receptor potential cation channel subfamily V member... 4 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448799 CHEMBL568565 Bioactive AGN-PC-00ED4G
CFAMM00448798 CHEMBL567714 Bioactive AGN-PC-00C2TD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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