CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18699
Family Name Prostaglandin E2 receptor EP3 subtype ligand N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[3-(naphthalen-2-ylmethyl)-1H-indol-4-yl]propanamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00448820 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP3 subtype Ligand DG041 Superfamily
Class Class 867

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP3 subtype Ligand DG041 Family 9 16
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
NF-kappa-B Inhibitor 5-bromo-n-(quinolin-8-yl)thiophene-2-sulf... 2 5
5-hydroxytryptamine receptor 6 ligand SureCN3147604 family 7 6
5-hydroxytryptamine receptor 6 ligand 1-(5-bromothiophen-2-yl)... 4 0
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00448822 CHEMBL585766 Bioactive N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[1-methyl-3-(naphthalen-2-ylmethyl)indol-4-yl]propanamide
CFAMM00448821 CHEMBL584492 Bioactive (E)-N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[3-(naphthalen-2-ylmethyl)-1H-indol-4-yl]prop-2-enamide
CFAMM00448820 CHEMBL567905 Bioactive N-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[3-(naphthalen-2-ylmethyl)-1H-indol-4-yl]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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