CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18700
Family Name Neutrophil elastase inhibitor 1-[4-(1,3-benzoxazol-2-ylsulfanylmethyl)phenyl]-3,3-diethylazetidine-2,4-dione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00448824 Functional Category Bioactive
Superfamily Thyrotropin receptor and Huntingtin Binder Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma Ligand SB-213... 2 54
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 7 1
Sigma non-opioid intracellular receptor 1 ligand 2-[4-(4-cyclo... 2 5
Reverse transcriptase/RNaseH inhibitor AC1LAJTX family 2 0


External ID

Functional Category

Molecule Name

CFAMM00448825 CHEMBL568217 Bioactive 2-[[4-(3,3-diethyl-2,4-dioxoazetidin-1-yl)phenyl]methylsulfanyl]-1,3-benzoxazole-5-carboxylic acid
CFAMM00448824 CHEMBL567956 Bioactive 1-[4-(1,3-benzoxazol-2-ylsulfanylmethyl)phenyl]-3,3-diethylazetidine-2,4-dione
CFAMM00448823 CHEMBL583408 Bioactive 1-[2-(1,3-benzoxazol-2-ylsulfanylmethyl)phenyl]-3,3-diethylazetidine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



72724 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543