CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18719
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-PC-07B1DR family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00448919 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 10
Class Class 3208

Cousin Family NamesSeedsMembers
DNA Binder Elliptinium Acetate Family 11 116
Citric Acid family 2 58
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 4
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
E3 ubiquitin-protein ligase Mdm2 Inhibitor NSC-66811 Family 4 27
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-0886S... 1 18
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 10
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Delta-type opioid receptor and Kappa-type opioid receptor liga... 4 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Transient receptor potential cation channel subfamily V member... 1 5
Proto-oncogene tyrosine-protein kinase receptor Ret ligand Sur... 1 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aR... 3 6
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
Mitogen-activated protein kinase 14 inhibitor (4E)-4-[3-amino-... 1 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aS... 2 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 4
Thioredoxin glutathione reductase and Nuclear receptor ROR-gam... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448922 CHEMBL602264 Bioactive AGN-PC-07RBGZ
CFAMM00448914 CHEMBL568822 Bioactive AGN-PC-07CQJP
CFAMM00448920 CHEMBL570187 Bioactive AGN-PC-07CQJM
CFAMM00448919 CHEMBL599635 Bioactive AGN-PC-07B1DR
CFAMM00448918 CHEMBL599636 Bioactive AGN-PC-07B1DQ
CFAMM00448917 CHEMBL599841 Bioactive AGN-PC-07RBHS
CFAMM00448916 CHEMBL602065 Bioactive (6S)-6-[propyl-[2-(4-quinolin-4-ylpiperazin-1-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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