CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18735
Family Name Receptor tyrosine-protein kinase erbB-2 and Disintegrin and metalloproteinase domain-containing protein 10 ligand [(5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)piperidin-3-yl] pyrrolidine-1-carboxylate family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00448975 Functional Category Bioactive
Superfamily Receptor tyrosine-protein kinase erbB-2 and Disintegrin and metalloproteinase domain-containing protein 10 ligand [(5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)piperidin-3-yl] pyrrolidine-1-carboxylate Superfamily
Class Class 5270

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 13
Receptor tyrosine-protein kinase erbB-2 and Disintegrin and me... 1 0
Disintegrin and metalloproteinase domain-containing protein 10... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448975 CHEMBL569388 Bioactive [(5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)piperidin-3-yl] pyrrolidine-1-carboxylate
CFAMM00448977 CHEMBL585304 Bioactive [(3R,5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)piperidin-3-yl] pyrrolidine-1-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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