CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18737
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene-2H-1,2,4-oxadiazol-3-yl)phenyl]-1H-benzimidazole-4-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00448986 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Serine/threonine-protein kinase Chk2 Binder Superfamily
Class Class 2756

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Tubulin beta chain Inhibitor Mebendazole Family 12 84
BIBT986 family 7 96
CC-486 family 7 103
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Telomerase reverse transcriptase Inhibitor NSC-745794 Family 3 1
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 2
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Histamine H3 receptor ligand SureCN2878688 family 8 1
Serine/threonine-protein kinase Chk2 inhibitor SureCN3922132 f... 3 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(1,2-oxazol-5-yl... 2 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077DC5 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00448986 CHEMBL569636 Bioactive 2-[4-(5-sulfanylidene-2H-1,2,4-oxadiazol-3-yl)phenyl]-1H-benzimidazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27030 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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