CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1874
Family Name Coagulation factor X inhibitor (3R,4R)-3-N-(5-chloropyridin-2-yl)-1-(2,2-difluoroethyl)-4-N-[2-fluoro-4-(2-oxopyridin-1-yl)phenyl]pyrrolidine-3,4-dicarboxamide family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00328418 Functional Category Bioactive
Superfamily Coagulation factor X and Neuropeptide Y-Y2 receptor Binder Superfamily
Class Class 846

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Transient receptor potential cation channel subfamily V member... 3 2
Transient receptor potential cation channel subfamily V member... 2 0


External ID

Functional Category

Molecule Name

CFAMM00328415 CHEMBL1221916 Bioactive SureCN4453417
CFAMM00328419 CHEMBL1221967 Bioactive SureCN4445000
CFAMM00328418 CHEMBL1221913 Bioactive (3R,4R)-3-N-(5-chloropyridin-2-yl)-1-(2,2-difluoroethyl)-4-N-[2-fluoro-4-(2-oxopyridin-1-yl)phenyl]pyrrolidine-3,4-dicarboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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