CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18751
Family Name Angiopoietin-1 receptor and Tyrosine-protein kinase Lck ligand aminoisoquinoline, 16 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00449018 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 1151

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Adenosine kinase inhibitor SureCN8183719 family 2 3
Platelet-activating factor receptor ligand Foropafant family 2 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 3 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449018 CHEMBL570573 Bioactive aminoisoquinoline, 16

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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