CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1877
Family Name Sonic hedgehog protein inhibitor 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00328438 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Mitogen-activated protein kinase 11 Binder Superfamily
Class Class 718

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-[4... 4 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Coagulation factor X inhibitor AGN-PC-030DHH family 1 0
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328438 CHEMBL1221983 Bioactive 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide
CFAMM00328433 CHEMBL2160030 Bioactive 3,4-dichloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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