CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18773
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[2-[(3R)-3-[2-(2-aminopyridin-4-yl)ethyl]-2-oxopiperidin-1-yl]acetyl]amino]pent-4-ynoic acid family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00449075 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 12
Class Class 639

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelegatran Family 8 157
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
XL-888 family 16 85
Class II cytokine receptor Ligand IL-10 Family 7 45
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Integrin beta-3 Inhibitor Elarofiban Family 28 45
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03RR5Q f... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2833591 f... 4 6
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-isoquinolin-1-y... 3 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-4-methy... 2 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[3-(2... 4 2
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453385 ... 5 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[4-(... 3 0
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[4-[[... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449076 CHEMBL57191 Bioactive (3S)-3-[[2-[(3R)-1-[2-(2-aminopyridin-4-yl)ethyl]-2-oxopiperidin-3-yl]acetyl]amino]pent-4-ynoic acid
CFAMM00449075 CHEMBL57192 Bioactive (3S)-3-[[2-[(3R)-3-[2-(2-aminopyridin-4-yl)ethyl]-2-oxopiperidin-1-yl]acetyl]amino]pent-4-ynoic acid
CFAMM00449077 CHEMBL59020 Bioactive (3S)-3-[[2-[2-(2-aminopyridin-4-yl)ethyl]-3-oxo-1H-isoindole-5-carbonyl]amino]pent-4-ynoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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