CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18817
Family Name C-C chemokine receptor type 8 and Potassium voltage-gated channel subfamily H member 2 ligand [9-[[3-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00449272 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 8
Class Class 2449

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
G-protein coupled bile acid receptor 1 ligand 2-ethyl-6-[3-[4-... 4 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449272 CHEMBL574655 Bioactive [9-[[3-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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