CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18819
Family Name Tyrosine-protein kinase receptor Tie-1 and Receptor-type tyrosine-protein kinase FLT3 ligand AST 487 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00256331 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Binder Superfamily 2
Class Class 850

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
SB1518 family 7 103
E7050 family 2 13
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Hepatocyte growth factor receptor Ligand BMS-777607 Family 10 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN97387... 4 1
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... 2 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 6 13
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 0
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 0
Transient receptor potential cation channel subfamily V member... 1 3
Platelet-derived growth factor receptor beta ligand SureCN2919... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27038 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543