CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18822
Family Name Tyrosine-protein kinase ZAP-70 inhibitor AGN-PC-07CO7Z family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00449282 Functional Category Bioactive
Superfamily Insulin receptor and ALK tyrosine kinase receptor Binder Superfamily
Class Class 1334

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 6
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... 3 7
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449282 CHEMBL575048 Bioactive AGN-PC-07CO7Z

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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