CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18825
Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor pyrazolo pyrimidine, 5d family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00449293 Functional Category Bioactive
Superfamily cAMP and Prelamin-A/C Binder Superfamily 4
Class Class 2087

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449292 CHEMBL575710 Bioactive pyrazolo pyrimidine, 5c
CFAMM00449293 CHEMBL575501 Bioactive pyrazolo pyrimidine, 5d

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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