CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18833
Family Name Collagenase 3 inhibitor SureCN1316041 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00449310 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Nonstructural protein 1 Binder Superfamily
Class Class 3226

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor Relacatib Family 26 32
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 1 3
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Cytochrome P450 2C19 and Inositol monophosphatase 1 inhibitor ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Histamine H3 receptor ligand SureCN2784306 family 5 3
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 1 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
Cathepsin K and Cathepsin L1 inhibitor AC1NR9VX family 2 2
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-073HN6 f... 1 1
Substance-P receptor ligand SureCN2139814 family 7 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 1
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 3 0
RAC-alpha serine/threonine-protein kinase inhibitor Isoquinoli... 1 0
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Rho-associated protein kinase 2 inhibitor SureCN13457632 family 1 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 12
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Collagenase 3 inhibitor SureCN1318719 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449307 CHEMBL578574 Bioactive SureCN1317049
CFAMM00449310 CHEMBL584683 Bioactive SureCN1316041
CFAMM00449309 CHEMBL578351 Bioactive SureCN1316337
CFAMM00449308 CHEMBL576213 Bioactive SureCN1316938

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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