CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18838
Family Name Cholinesterase inhibitor [(3R,3aR,6S,6aR)-6-(ethylcarbamoyloxy)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl] 2-hydroxybenzoate family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00449324 Functional Category Bioactive with Natural Product
Superfamily Vacuolar H+-ATPase Inhibitor Lobatamide A Superfamily
Class Class 1572

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Cholinesterase Inhibitor Isosorbide-2-(benzylcarbamate)-5-benz... 4 11
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Protein kinase C delta type and Protein kinase C alpha type in... 1 10
Cholinesterase and Acetylcholinesterase inhibitor [(3R,3aR,6S,... 1 0
Benzopyrans Metabolite (-)-trans-3,4-Dihydro-4,8-dihydroxy-3-m... 1 0
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3


External ID

Functional Category

Molecule Name

CFAMM00449325 CHEMBL577112 Bioactive [(3R,3aR,6S,6aR)-6-(dimethylcarbamoyloxy)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl] 2-hydroxybenzoate
CFAMM00449324 CHEMBL576529 Bioactive [(3R,3aR,6S,6aR)-6-(ethylcarbamoyloxy)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-yl] 2-hydroxybenzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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