CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18844
Family Name P2Y purinoceptor 12 inhibitor pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-(propan-2-ylcarbamoylamino)pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate family
No. of Seeds 18 No. of Other Members 0
Family Centroid CFAMM00449386 Functional Category Bioactive
Superfamily P2Y purinoceptor 12 Binder Superfamily 3
Class Class 639

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
CP-18770 family 6 27
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Endothelin B receptor Ligand IRL-2500 Family 34 87
Cholecystokinin receptor type A ligand A-65186 family 2 6
Dihydrofolate reductase and Thymidylate synthase inhibitor 2-[... 10 5
Pol polyprotein and Cathepsin D inhibitor N-[(1S)-1-[(2R,3S)-3... 2 1
Hematopoietic prostaglandin D synthase inhibitor 4-(3-methylis... 1 7
Neuromedin-K receptor and Potassium voltage-gated channel subf... 13 2
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Motilin receptor ligand SureCN2768052 family 3 0
Cholecystokinin receptor type A ligand (4R)-5-(dipentylamino)-... 1 11
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-[3-(dimethylamino)... 106 49
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
P2Y purinoceptor 12 inhibitor (4S)-4-[(4,6-diphenylpyridine-2-... 1 0
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-(2-aminoethyl)pipe... 17 2
P2Y purinoceptor 12 inhibitor (4S)-4-[[6-[4-[2-(methylamino)-2... 51 8
P2Y purinoceptor 12 inhibitor (4S)-5-oxo-5-(4-pentoxycarbonylp... 5 0
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(4-amino-... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449389 CHEMBL578482 Bioactive pentyl 4-[(2S)-2-[[4-[[2-(dimethylamino)acetyl]amino]-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449382 CHEMBL591712 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-(piperidin-4-ylmethylcarbamoylamino)pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
CFAMM00449395 CHEMBL577433 Bioactive pentyl 4-[(2S)-2-[(4-acetamido-6-phenylpyridine-2-carbonyl)amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449388 CHEMBL599634 Bioactive tert-butyl (4S)-5-oxo-5-[4-(pentylcarbamothioyl)piperazin-1-yl]-4-[(6-phenylpyridine-2-carbonyl)amino]pentanoate
CFAMM00449381 CHEMBL577236 Bioactive pentyl 4-[(2S)-2-[[4-[(4-methylpiperazine-1-carbonyl)amino]-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449394 CHEMBL604497 Bioactive tert-butyl (4S)-5-[4-(butylcarbamothioyl)piperazin-1-yl]-5-oxo-4-[(6-phenylpyridine-2-carbonyl)amino]pentanoate
CFAMM00449387 CHEMBL577854 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-2-[[4-(morpholine-4-carbonylamino)-6-phenylpyridine-2-carbonyl]amino]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449380 CHEMBL592165 Bioactive pentyl 4-[(2S)-2-[[4-[[2-(methylamino)acetyl]amino]-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449393 CHEMBL592407 Bioactive pentyl 4-[(2S)-2-[[4-[(4-methoxypiperidine-1-carbonyl)amino]-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449386 CHEMBL578080 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-(propan-2-ylcarbamoylamino)pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
CFAMM00449379 CHEMBL592164 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-2-[[4-(oxane-4-carbonylamino)-6-phenylpyridine-2-carbonyl]amino]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449392 CHEMBL577653 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-[(2,2,2-trifluoroacetyl)amino]pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
CFAMM00449385 CHEMBL579094 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-(piperidine-1-carbonylamino)pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
CFAMM00449378 CHEMBL592166 Bioactive pentyl 4-[(2S)-2-[[4-[[2-(dimethylamino)-2-oxoethyl]carbamoylamino]-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449391 CHEMBL592410 Bioactive pentyl 4-[(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-[[6-phenyl-4-(piperidin-4-ylmethoxycarbonylamino)pyridine-2-carbonyl]amino]pentanoyl]piperazine-1-carboxylate
CFAMM00449384 CHEMBL578094 Bioactive pentyl 4-[(2S)-2-[[4-(2-methoxyethoxycarbonylamino)-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449390 CHEMBL578507 Bioactive pentyl 4-[(2S)-2-[[4-(3-aminopropoxycarbonylamino)-6-phenylpyridine-2-carbonyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
CFAMM00449383 CHEMBL599843 Bioactive tert-butyl (4S)-5-[4-(ethylcarbamothioyl)piperazin-1-yl]-5-oxo-4-[(6-phenylpyridine-2-carbonyl)amino]pentanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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